Hyperostosis Frontalis Interna is characterized by the thickening of the frontal bone of the skull. It is not clear that this disorder is actually rare. Some clinicians. Hyperostosis frontalis interna is characterised by benign overgrowth of the inner table of the frontal bone. It is seen most commonly in older females. The etiology . chronic, severe anaemia · hyperparathyroidism · acromegaly · osteopetrosis · hyperostosis frontalis interna; long-term phenytoin use; genetic diseases (rare).
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Central Nervous SystemMusculoskeletal. Diabetes Insipidus is due to an abnormality of anti-diuretic hormone vasopresin or ADH originating in the posterior lobe of the pituitary gland. The patient met the criteria of Morgagni-Stewart-Morel syndrome to manifest the presence of hyperostosis frontalis interna with metabolic, endocrine and neuropsychiatric manifestations.
Hyperostosis of the skull (differential) | Radiology Reference Article |
The etiology is unknown. This disorder causes a general enlargement and distortion of all the features. Synonyms or Alternate Spellings: Affected Populations Hyperostosis Frontalis Interna affects females 9 times more ibterna than males.
It is not clear that this disorder is actually rare. Many people have no apparent symptoms. About News Events Contact. In the case of Farinelli, castration was probably responsible for the onset and development of this lesion. Crouzon Disease is a genetic disorder characterized by abnormalities in the skull, face, and brain caused by premature hardening of the skull.
Case 8 Case 8. Case 5 Case 5. The content of the website and databases of the National Organization for Rare Disorders NORD is copyrighted and may not be reproduced, copied, downloaded or disseminated, in any way, for any commercial or public purpose, without prior written authorization and approval from NORD.
The importance of this condition stems mainly fdontal the necessity of not mistaking it for pathology. Most conspicuously affected are the extremities, jaws, and face.
Rare Disease Database
Hyperostosis associated with meningioma of the cranial base: Case 2 Case 2. Articles Cases Courses Quiz. They are not necessary for a differential diagnosis:.
It ftontal not known if the disorder is autosomal dominant or X-linked. Primer of Diagnostic Imaging. Paget’s disease Case 4: Support Radiopaedia and see fewer ads. Symptoms of this disorder may be tripping, falling, difficulty in moving the neck, lack of facial expression and a nasal sounding voice. Human traits, including the classic genetic diseases, ftontal the product of the interaction of two genes, one received from the father and one from the mother.
The major feature of Hyperostosis Frontalis Interna is excessive growth or thickening interja the frontal bone of the head. The famous castrato singer Farinelli was exhumed by our research group in July for the purpose of gaining some insight into his biological profile through a study of his skeletal remains.
Diffuse Paget’s disease of bone metastatic disease, especially prostate carcinoma chronic, severe anaemia hyperparathyroidism acromegaly osteopetrosis hyperostosis frontalis interna long-term phenytoin use genetic diseases rare Hi;erostosis disease frontometaphyseal dysplasia craniodiaphysial dysplasia Focal meningioma fibrous dysplasia Paget’s disease of bone metastatic disease, especially prostate carcinoma esthesioneuroblastoma: During this hospital stay the presence of grade I obesity, hyperglycemia, hypertriglyceridemia and hyperuricemia was documented.
Vision disturbances and deafness may develop in some cases.
Hyperostosis frontalis interna | Radiology Reference Article |
This condition consists in a symmetrical thickening of the inner table of the bone. Thank you for updating your details. Hershkovitz I, et al. Torres MA, et al. The epidemiology of HFI shows that it is relatively common in postmenopausal women but very rare in men. It can cause mental deficiency and loss of hair.